Ingredient pairing

Can you mix Glycolic acid and Retinyl Retinoate?

ClashThese clash.

Glycolic acidRetinyl Retinoate

Retinoids and exfoliants both speed up cell turnover, so together they tend to stack irritation and can wear down your barrier.

Do this: Use them on alternate nights rather than the same evening.

☀ Morning

Nothing here

☾ Evening

Glycolic acidRetinyl Retinoate

Use on alternate nights, not the same evening.

Glycolic acidWorth paying for
Efficacy9
Anti-aging7
Brightening4

Skip if: sensitive, compromised barrier, rosacea

Ask your doctor in pregnancy
Retinyl RetinoatePromising, not proven
Efficacy8
Anti-aging8
Brightening4

Skip if: pregnancy, breastfeeding

Not in pregnancy

General guidance, not medical advice. When in doubt, introduce one product at a time.