Ingredient pairing

Can you mix Lactobionic Acid and Tretinoin?

ClashThese clash.

Lactobionic AcidTretinoin

Retinoids and exfoliants both speed up cell turnover, so together they tend to stack irritation and can wear down your barrier.

Do this: Use them on alternate nights rather than the same evening.

☀ Morning

Nothing here

☾ Evening

Lactobionic AcidTretinoin

Use on alternate nights, not the same evening.

Lactobionic AcidSolid and proven
Hydration10
Efficacy8
Barrier8
TretinoinWorth paying for
Efficacy10
Acne10
Anti-aging10

Skip if: pregnancy, breastfeeding, very sensitive

Not in pregnancy

General guidance, not medical advice. When in doubt, introduce one product at a time.