Ingredient glossary

Tretinoin

INCI: Tretinoin · Also: Retinoic Acid, All-trans Retinoic Acid

Worth paying for

Strong results with strong evidence behind them. This is one genuinely worth having in a formula.

Does Tretinoin clash with what you already use? Check it →

What it does

  • anti aging
  • anti acne
  • texture
  • brightening

strong evidenceSystematic reviews consistently show tretinoin outperforms other topical agents for photoaging and acne, but tolerability limits its cosmetic use.

On a label: works best above 0.025%.

Who it's for, and who should skip it

Tends to suit

  • acne prone
  • photoaged

Approach with care

  • pregnancy
  • breastfeeding
  • very sensitive
  • Clogs poresLow
  • Irritation riskHigh

Pregnancy: Not for use during pregnancy or breastfeeding.

Plays well with

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Educational information about a cosmetic ingredient, not medical advice.