Ingredient pairing

Can you mix Tretinoin and Vitamin B3?

Fine togetherThey're fine together.

TretinoinVitamin B3

These two actually work well together, and are often formulated side by side.

Routine: You can use these together, morning or night.

TretinoinWorth paying for
Efficacy10
Acne10
Anti-aging10

Skip if: pregnancy, breastfeeding, very sensitive

Not in pregnancy
Vitamin B3Worth paying for
Efficacy9
Barrier9
Acne8

Skip if: very sensitive in high

General guidance, not medical advice. When in doubt, introduce one product at a time.