Ingredient comparison

Matrixyl Synthe'6 vs Syn-Ake: which one is right for your skin?

Same comparison whichever way you searched it: Syn-Ake vs Matrixyl Synthe'6.

Short answer: Honestly, either one works. Choose by your skin type and what your routine already has.

Chemical structure of Matrixyl Synthe'6 (Palmitoyl Tripeptide-38)Matrixyl Synthe'6Promising, not proven
Chemical structure of Syn-Ake (Dipeptide Diaminobutyroyl Benzylamide Diacetate)Syn-AkePromising, not proven
5
Efficacy
5
2
Barrier
1
5
Anti-aging
5
Matrixyl Synthe'6 versus Syn-Ake, compared
ComparedMatrixyl Synthe'6Syn-Ake
PotencySimilarSimilar
Evidenceemerging evidenceemerging evidence
Irritation riskLowLow
Clogs poresLowLow
In pregnancyConsidered safeConsidered safe
On a labelusually effective at 1-2%usually effective at 1-4%

So which should you pick?

These two are close enough to be near-interchangeable. Honestly, either one works. Choose by your skin type and what your routine already has.

No known clash between these two. If you want both, you can layer them; introduce one at a time.

Check these two in the tool →Or decode a whole product label →

From our dataNeither has to be the answer: 49 other ingredients in our glossary share a family with these two.

Matrixyl Synthe'6 vs Syn-Ake, answered

Which is stronger, Matrixyl Synthe'6 or Syn-Ake?

They are close in strength: Matrixyl Synthe'6 and Syn-Ake score similarly on efficacy. Choose by skin type rather than power.

Is Matrixyl Synthe'6 or Syn-Ake better for sensitive skin?

Both carry a similar irritation risk (low). Patch test either one before using it daily.

Can you use Matrixyl Synthe'6 and Syn-Ake together?

There is no known clash between them. You can layer them if you like, just introduce one at a time.

General guidance, not medical advice. Read the full pages on Matrixyl Synthe'6 and Syn-Ake.