Ingredient glossary

Cyclohexasiloxane

What Cyclohexasiloxane does for your skin, who it suits, and what to watch for.

INCI: Cyclohexasiloxane · Also: D6

Solid and proven

In short: Cyclohexasiloxane delivers softening and volatile texture, suits most skin types, and the evidence behind it is moderate.

What it does
Softening, volatile texture
Best for
Most skin types
Evidence
Moderate
How long
Straight away
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The molecule

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The Glow take

A comfort ingredient, and none the worse for it.

Cyclohexasiloxane is here for feel and moisture, softening the skin and slowing water loss. More comfort than correction.

— Maya

What it does

  • softening
  • volatile texture

moderate evidenceUsed alongside other silicones to tune dry-down and playtime; considered low-irritation in cosmetic use.

On a label: usually effective at 2-20%.

Who it's for, and who should skip it

Tends to suit

  • oily
  • combo
  • normal

Approach with care

  • very dry needing occlusive
  • Clogs poresLow
  • Irritation riskLow

How it fits each skin type

  • DryTake care
  • CombinationSuits
  • OilySuits
  • SensitiveSuits

Where it fits in your routine

WhenMorning and evening
Where in the orderAfter your actives, to seal everything in

This one works on contact — there is nothing to wait for.

What that covers, and what it does not

Measured on: Slip and weightless dry-down during application, from a volatile silicone film.

The same volatile cyclic siloxane chemistry as D5 with one extra unit and a slightly longer play-time before it evaporates; the slip is present on contact and gone after dry-down. Used at 2-20% chiefly to tune the feel of other silicones. There is even less ingredient-specific literature than for D5, and no study reports a timed skin outcome.

No efficacy-timing trial identified. Ingredient physical chemistry (volatile cyclic siloxane), read-across from D5.

Plays well with

  • other silicones
  • humectants

Cyclohexasiloxane, answered

Is Cyclohexasiloxane safe during pregnancy?

Yes. Cyclohexasiloxane is considered safe to use during pregnancy and breastfeeding. As with anything, if you are unsure it is worth a quick word with your doctor or midwife.

Who should avoid Cyclohexasiloxane?

Approach Cyclohexasiloxane with care if any of these apply to you: very dry needing occlusive.

What concentration of Cyclohexasiloxane actually works?

Cyclohexasiloxane tends to do its job in the 2 to 20% range. Much lower and it is likely underdosed.

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Sources & how we reviewed this

Last reviewed August 2026. Educational information about a cosmetic ingredient, not medical advice.