Ingredient glossary
Dipotassium Glycyrrhizate
On your shelf ✓What Dipotassium Glycyrrhizate does for your skin, who it suits, and what to watch for.
INCI: Dipotassium Glycyrrhizate · Also: Dipotassium Glycyrrhizin, Licorice Root Derivative
In short: Dipotassium Glycyrrhizate delivers soothing and anti inflammatory, suits sensitive skin best, and the evidence behind it is moderate.
- What it does
- Soothing, anti inflammatory
- Best for
- Sensitive skin
- Evidence
- Moderate
- How long
- Never measured
The molecule
The three pieces are meant to be apart. Dipotassium Glycyrrhizate is a salt, and its parts are held to each other by opposite charges rather than by a bond.
The Glow take
Genuinely worth a spot in your routine.
When your goal is repairing a stressed moisture barrier, Dipotassium Glycyrrhizate pulls genuine weight, with a solid amount of evidence behind it. It tends to suit sensitive skin best.
— Maya
What it does
- soothing
- anti inflammatory
- barrier support
- anti redness
moderate evidenceRandomized parallel group studies of emollients containing dipotassium glycyrrhizin show significant reductions in SCORAD pruritus scores and flare frequency in adults with atopic dermatitis without notable adverse events.
On a label: usually effective at 0.1-0.5%.
Who it's for, and who should skip it
Tends to suit
- sensitive
- very sensitive
- atopic
- acne prone
- compromised barrier
Approach with care
- rare licorice allergy
- Clogs poresLow
- Irritation riskLow
How it fits each skin type
- DryNeutral
- CombinationNeutral
- OilyNeutral
- SensitiveSuits
Often chosen for atopic, acne prone, compromised barrier. Take extra care if any of these apply to you: rare licorice allergy.
Where it fits in your routine
Nobody has published how long this takes to work.
What is known, and what is missing
Measured on: SCORAD and itch NRS in atopic dermatitis.
The 2025 randomised parallel-controlled study of dipotassium-glycyrrhizin emollients in adult atopic dermatitis compares emollient use against no emollient, with SCORAD read at 12 weeks after 8 weeks of use; an emollient base improves atopic skin on its own, so neither the effect nor its timing separates out to the licorice salt. No vehicle-controlled trial of the salt alone, at the 0.1-0.5% cosmetics use, reports when redness or itch changes.
Randomized parallel-controlled study of dipotassium glycyrrhizin emollients in adult atopic dermatitis, Pak J Med Sci 2025 (PMID not verified)
Plays well with
- panthenol
- beta glucan
- ceramides
Dipotassium Glycyrrhizate, answered
Is Dipotassium Glycyrrhizate safe during pregnancy?
Yes. Dipotassium Glycyrrhizate is considered safe to use during pregnancy and breastfeeding. As with anything, if you are unsure it is worth a quick word with your doctor or midwife.
Who should avoid Dipotassium Glycyrrhizate?
Approach Dipotassium Glycyrrhizate with care if any of these apply to you: rare licorice allergy.
What concentration of Dipotassium Glycyrrhizate actually works?
Dipotassium Glycyrrhizate tends to do its job in the 0.1 to 0.5% range. Much lower and it is likely underdosed.
Can you mix Dipotassium Glycyrrhizate with
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