Ingredient glossary

Glutathione

INCI: Glutathione · Also: Reduced Glutathione, GSH

Decent support

A reasonable supporting ingredient. It helps a formula without being the star.

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What it does

  • antioxidant
  • brightening

moderate evidenceSystematic reviews and small RCTs indicate that topical two percent oxidized glutathione and oral five hundred milligram dosing can reduce melanin index and improve some aging markers in sun exposed skin but data quality and consistency are limited.

On a label: usually effective at 2%.

Who it's for, and who should skip it

Tends to suit

  • pigmentation
  • photoaged
  • normal
  • combo

Approach with care

No specific group flagged to avoid it.

  • Clogs poresLow
  • Irritation riskLow

Pregnancy: Check with your doctor before using during pregnancy or breastfeeding.

Plays well with

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Educational information about a cosmetic ingredient, not medical advice.