Ingredient glossary

Rigin

What Rigin does for your skin, who it suits, and what to watch for.

INCI: Palmitoyl Tetrapeptide-7 · Also: Palmitoyl Tetrapeptide-3

Promising, not proven

In short: Rigin delivers anti inflammatory and anti-aging support, suits most skin types, and the evidence behind it is limited.

What it does
Anti inflammatory, anti aging
Best for
Most skin types
Evidence
Limited
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The molecule

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The Glow take

Nice to have, and nothing to overthink.

Rigin plays a quiet supporting role, rounding out a formula rather than being the reason you buy it.

— Maya

What it does

  • anti inflammatory
  • anti aging

weak evidenceReviews of the published work find a single human study and no randomised controlled trial; the rest is in vitro cytokine data from Sederma, which sells it as half of the Matrixyl 3000 pair.

Who it's for, and who should skip it

Tends to suit

  • normal
  • combo
  • photoaged

Approach with care

No specific group flagged to avoid it.

  • Clogs poresLow
  • Irritation riskLow

How it fits each skin type

  • DrySuits
  • CombinationSuits
  • OilySuits
  • SensitiveSuits

Often chosen for photoaged.

Where it fits in your routine

WhenMorning or evening
Where in the orderAfter cleansing, before your moisturizer

Plays well with

  • other peptides
  • humectants

Rigin, answered

Is Rigin safe during pregnancy?

Yes. Rigin is considered safe to use during pregnancy and breastfeeding. As with anything, if you are unsure it is worth a quick word with your doctor or midwife.

Who should avoid Rigin?

No specific group is flagged to avoid Rigin. It is well tolerated by most skin. Still, introduce anything new one product at a time.

What concentration of Rigin actually works?

Its concentration is rarely printed on the label, so use the ingredient list as your clue: near the top third it is likely doing real work, near the bottom it is more of a sprinkle.

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Sources & how we reviewed this

Last reviewed August 2026. Educational information about a cosmetic ingredient, not medical advice.