Ingredient glossary

Trisodium EDDS

What Trisodium EDDS does for your skin, who it suits, and what to watch for.

INCI: Trisodium Ethylenediamine Disuccinate · Also: EDDS

Minor player

In short: Trisodium EDDS delivers chelation and oxidative stability, plays a broad, supporting role, and the evidence behind it is strong.

What it does
Chelation, oxidative stability
Best for
A broad, supporting role
Evidence
Strong
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The molecule

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The Glow take

Nice to have, and nothing to overthink.

Trisodium EDDS plays a quiet supporting role, rounding out a formula rather than being the reason you buy it.

— Maya

What it does

  • chelation
  • oxidative stability
  • preservation

strong evidenceThe CIR panel reviewed it together with tetrasodium iminodisuccinate in 2023 and found it safe at reported use levels up to 0.64 percent with no clinically relevant irritation or sensitization.

Who it's for, and who should skip it

Tends to suit

No specific skin type. It is a broadly used ingredient.

Approach with care

  • rare allergy
  • Irritation riskLow

How it fits each skin type

  • DryNeutral
  • CombinationNeutral
  • OilyNeutral
  • SensitiveNeutral

Take extra care if any of these apply to you: rare allergy.

Where it fits in your routine

WhenMorning or evening
Where in the orderAfter cleansing, before your moisturizer

Plays well with

  • preservatives

Trisodium EDDS, answered

Is Trisodium EDDS safe during pregnancy?

Yes. Trisodium EDDS is considered safe to use during pregnancy and breastfeeding. As with anything, if you are unsure it is worth a quick word with your doctor or midwife.

Who should avoid Trisodium EDDS?

Approach Trisodium EDDS with care if any of these apply to you: rare allergy.

What concentration of Trisodium EDDS actually works?

Its concentration is rarely printed on the label, so use the ingredient list as your clue: near the top third it is likely doing real work, near the bottom it is more of a sprinkle.

Does it clog pores?

0/5
Non-comedogenic

No comedogenicity studies exist for this water-soluble chelator; rated 0 here.

  • This rating comes from old lab tests on the isolated ingredient, not the finished product.
  • The full formula, how much is used, and your own skin all matter more than one number.
  • If you are acne-prone it is worth noticing, not a reason to avoid it on sight.

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Sources & how we reviewed this

  1. CIR safety review EDDS and iminodisuccinate 2023summary page only, the document itself was not read

Last reviewed August 2026. Educational information about a cosmetic ingredient, not medical advice.