Ingredient glossary

Argireline

INCI: Acetyl Hexapeptide-8 · Also: Acetyl Hexapeptide-3

Promising, not proven

Early signs are interesting, but the proof is not in yet. Worth watching, not worth a premium.

Does Argireline clash with what you already use? Check it →

What it does

  • anti aging
  • wrinkle smoothing

emerging evidenceAvailable studies and reviews describe reductions in wrinkle depth at around ten percent solution but many are small and industry sponsored so effect size is uncertain.

On a label: usually effective at 5-10%.

Who it's for, and who should skip it

Tends to suit

  • normal
  • combo
  • photoaged

Approach with care

No specific group flagged to avoid it.

  • Clogs poresLow
  • Irritation riskLow

Plays well with

  • other peptides
  • humectants
  • film formers

This, for every label you own

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Educational information about a cosmetic ingredient, not medical advice.