Medik8 Liquid Peptides

Serum~€52typical, July 2026

Our read, in one look

Glycerin is the reason to consider this serum, with Pro-vitamin B5 behind it.

The case for it

  • Glycerin, strong evidence for hydration
  • Pro-vitamin B5, strong evidence for the barrier
  • No fragrance, alcohol, silicones or parabens

Mind this

  • Morning or evening, whichever suits your routine
  • Add it on its own for a week or two, so you know what your skin is answering to
Best for dry, dehydrated, sensitive, normal skinFind it on amazon.com
Maya's read

Medik8 Liquid Peptides is a serum built around Glycerin, Hyaluronic acid and Pro-vitamin B5. It leans strongest on hydration, barrier repair. Best suited to dry, dehydrated and sensitive skin. Nothing in it we'd flag for most people.

Skip it if you already own something similar: it's a solid, honest basic rather than a must-have upgrade.

The formula, drawn

Every ingredient in label order, coloured by the job it does here.

19 of the 35 sit above the 1% line. The other 16, hatched, are each under 1%. Widths show the ORDER on the label and nothing else: the label never discloses amounts, so we never draw them.

  • Actives & signals
  • Hydrators
  • Texture & base
  • Preservation
  • Not in our library yet
  • No fragrance anywhere on the label

What it delivers

Hydration10
Barrier repair8
Brightening / tone3
Oil-control & blemishes2
Anti-aging6

How it feels A light, fast-absorbing texture that layers cleanly under the rest of your routine, with no greasy film. (estimated from the formula)

What's in it that matters

The molecule doing the workGlycerinHumectant · strong evidence

Classic humectant with strong evidence for improving skin hydration and supporting barrier when combined with emollients.

  • Hyaluronic acidHumectantstrong evidence

    Water-binding molecule that increases hydration; works best under occlusive/emollient layers to reduce evaporation.

  • Pro-vitamin B5Supporting Activestrong evidence

    Humectant and soothing ingredient that helps calm irritation and supports barrier repair and recovery.

  • Palmitoyl Tripeptide-1Active|Supporting Activemoderate evidence

    Collagen signaling tripeptide that supports firmness and elasticity when used with other peptides but human data mostly come from blend studies.

  • ArgirelineActive|Supporting Activeemerging evidence

    Topical peptide that targets expression lines by interfering with neurotransmitter release offering modest wrinkle smoothing with limited high quality clinical data.

  • Matrixyl Synthe'6Active|Supporting Activeemerging evidence

    Sold as Matrixyl synthe'6 and marketed on stimulating six matrix constituents at once. The placebo controlled data behind it is real, small, and all of it comes from its own manufacturer.

How to use it

Morning and/or night, after your thinner water-based steps and before heavier creams.

Where it acts

The same cross-section as our 500 dalton page, with this formula's actives on the layer each one works on. Depth is the anatomy's, never an ingredient's.

3 of this product's actives have a layer we can defend. 3 did not, so they are not on the diagram: no source and no honest derivation means no dot.

Against the average serum

HydrationBarrier repairBrighteningOil-controlAnti-aging
This productMedian serum (20 in catalogue)

It scores lower than the median serum on brightening.

On hydration, barrier repair and anti-aging it is level with the median, so that is not what sets it apart.

A median, not an average: one unusual formula should not move the middle. The numbers are the same 0 to 10 reads the comparison pages use.

The full ingredients list, decoded

Every ingredient on the label, in the order it appears (highest amount first). We link the 18 our library knows, name what each one does, and flag anything that can irritate or clog. The rest we leave plain, nothing is hidden.

All 35 ingredients, decoded
  1. Aqua (Water)Solvent (base)
  2. GlycerinHumectant
  3. Copper Heptapeptide-14 Pantothenate
  4. Heptapeptide-15 PalmitateEmollient (ester)
  5. Arginine/Lysine PolypeptideAmino acid (NMF)
  6. Carnosine
  7. Acetyl Hexapeptide-8Neuromodulating peptide
  8. Pentapeptide-18Neuromodulating peptide
  9. Palmitoyl Tripeptide-5
  10. Tetrapeptide-21
  11. Inulin
  12. Alpha-Glucan OligosaccharideHumectant (sugar)
  13. Lactic Acid/Glycolic Acid Copolymer
  14. PanthenolHumectant
  15. roughly the 1% lineThe rules only require descending order above 1%. From Ethylhexylglycerin down, these 16 can be listed in any order the brand likes, so position stops telling you anything.
  16. EthylhexylglycerinPreservative booster
  17. Hydroxypropyl Cyclodextrin
  18. Dunaliella Salina (Green Algae) ExtractBotanical extract
  19. Polysorbate 20Emulsifier
    mild irritant
  20. Caprylyl GlycolPreservative booster
  21. Citric AcidExfoliant
    mild irritant
  22. Glyceryl Caprylate
  23. PantolactoneSkin conditioning
  24. Phenylpropanol
  25. Polyvinyl Alcohol
  26. CarbomerThickener
  27. Potassium SorbatePreservative
  28. Sodium BenzoatePreservative
  29. Sorbic Acid
  30. PhenoxyethanolPreservative
    mild irritant
  31. Xanthan GumThickener
Copy the raw INCI list

Aqua (Water), Glycerin, Butylene Glycol, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Copper Heptapeptide-14 Pantothenate, Heptapeptide-15 Palmitate, Arginine/Lysine Polypeptide, Palmitoyl Tripeptide-38, Carnosine, Acetyl Hexapeptide-8, Pentapeptide-18, Palmitoyl Tripeptide-5, Tetrapeptide-21, Sodium Hyaluronate, Inulin, Alpha-Glucan Oligosaccharide, Lactic Acid/Glycolic Acid Copolymer, Panthenol, Ethylhexylglycerin, Hydroxypropyl Cyclodextrin, Dunaliella Salina (Green Algae) Extract, Polysorbate 20, Caprylyl Glycol, Citric Acid, Glyceryl Caprylate, Pantolactone, Phenylpropanol, Polyvinyl Alcohol, Carbomer, Potassium Sorbate, Sodium Benzoate, Sorbic Acid, Phenoxyethanol, Xanthan Gum

Read enough? Find it on amazon.com

We don't make or sell skincare of our own. So there's nothing here we're trying to push, just an honest read of whether this formula suits your skin.

Compare it with…

All 11 comparisons

Common questions

Is Medik8 Liquid Peptides good for dry skin?

By our read of the formula, it suits dry, dehydrated, sensitive skin. Medik8 Liquid Peptides is a serum built around Glycerin, Hyaluronic acid and Pro-vitamin B5. It leans strongest on hydration, barrier repair. Best suited to dry, dehydrated and sensitive skin. Nothing in it we'd flag for most people.

How do you use Medik8 Liquid Peptides?

Morning and/or night, after your thinner water-based steps and before heavier creams.

What are the key ingredients in Medik8 Liquid Peptides?

The actives that do the work are Glycerin, Hyaluronic acid, Pro-vitamin B5, Palmitoyl Tripeptide-1, Argireline, Matrixyl Synthe'6. The rest of the list is texture, preservatives and emulsifiers that hold the formula together.

Does Medik8 Liquid Peptides contain fragrance?

No. By our reading of the ingredient list it is fragrance-free, which is a plus for sensitive or reactive skin.

What the 3D scene shows

The scene shows Medik8 Liquid Peptides beside a cross-section of skin, with 2 of its ingredients drawn at the layer each one acts on and at one shared molecular scale: Glycerin and Pro-vitamin B5 in the stratum corneum, the dead outer layer where most skincare works. Depths come from the same sourced layer data as the rest of this site, and any ingredient whose layer is not established is left out rather than guessed.

Chemical structure of Glycerin
Building the scene…

This is skin, in section.

The molecules floating inside it are from this bottle, each at the layer it works on, drawn to one true scale. Drag to turn, pinch or scroll to zoom, tap a molecule for its evidence.

Skin in section· molecules from this formula · one true scale
tap it to decode ↻
Liquid PeptidesMedik8 · Serum · ~€52

Glycerin is the reason to consider this serum, with Pro-vitamin B5 behind it.

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