Head to head

La Roche-Posay Hyalu B5 Suractivated Serum vs Medik8 Liquid Peptides

Same comparison whichever way you searched it: Medik8 Liquid Peptides vs La Roche-Posay Hyalu B5 Suractivated Serum.

The bottom line

La Roche-Posay Hyalu B5 Suractivated Serum and Medik8 Liquid Peptides are close on what they deliver, so it comes down to your skin: Medik8 Liquid Peptides is the kinder pick for sensitive or reactive skin since it is fragrance-free.

La Roche-Posay Hyalu B5 Suractivated SerumLa Roche-PosayHyalu B5 Suractivated SerumSerum · ~$40See every ingredient in Hyalu B5 Suractivated Serum, decoded
Medik8 Liquid PeptidesMedik8Liquid PeptidesSerum · ~€52See every ingredient in Liquid Peptides, decoded

Which should you pick?

Pick Hyalu B5 Suractivated Serum if

  • you want the more affordable option

Pick Liquid Peptides if

  • your skin is sensitive or reacts to fragrance

What each delivers

HydrationBarrierBrighteningOil-controlAnti-aging
Hyalu B5 Suractivated SerumLiquid Peptides
  • Hydration
    1010
  • Barrier repair
    88
  • Brightening / tone
    33
  • Oil-control & blemishes
    32
  • Anti-aging
    76

Side by side

Hyalu B5 Suractivated SerumLiquid Peptides
TypeSerumSerum
Key activesGlycerin, Pro-vitamin B5, Hyaluronic acidGlycerin, Hyaluronic acid, Pro-vitamin B5
TextureA light, fast-absorbing texture that layers cleanly under the rest of your routine, with no greasy film.A light, fast-absorbing texture that layers cleanly under the rest of your routine, with no greasy film.
FragranceContains fragranceNone detected
Fungal-acne safeNot likelyNot likely
PregnancyNo flagged activesNo flagged actives
Ingredients32 listed35 listed
Price~$40~€52

What's in one but not the other

The molecule doing the work

Hyalu B5 Suractivated SerumGlycerin
Liquid PeptidesGlycerin

Better for…

  • Dryness & dehydrationEither works
  • Sensitive, reactive skinLiquid Peptides

La Roche-Posay Hyalu B5 Suractivated Serum is the cheaper of the two (~$40 vs ~€52).

Ready to pick one?

Affiliate links, so a purchase sends us a small commission at no extra cost to you. As an Amazon Associate, Glow Simplified earns from qualifying purchases. We make and sell nothing here, so the verdict above never bends toward a sale.

Common questions

Is La Roche-Posay Hyalu B5 Suractivated Serum or Medik8 Liquid Peptides better for sensitive, reactive skin?

For sensitive, reactive skin, Medik8 Liquid Peptides is the stronger pick by our read of the two formulas. La Roche-Posay Hyalu B5 Suractivated Serum and Medik8 Liquid Peptides are close on what they deliver, so it comes down to your skin: Medik8 Liquid Peptides is the kinder pick for sensitive or reactive skin since it is fragrance-free.

Which is cheaper, La Roche-Posay Hyalu B5 Suractivated Serum or Medik8 Liquid Peptides?

La Roche-Posay Hyalu B5 Suractivated Serum is the cheaper of the two (~$40 vs ~€52).

Can I use La Roche-Posay Hyalu B5 Suractivated Serum and Medik8 Liquid Peptides together?

They are both serums, so you would normally pick one rather than layer both in the same step. You can keep both and alternate them (morning and night, or on different days) if you like variety, but you do not need two.

Compare it with…

All 26 comparisons
Chemical structure of GlycerinChemical structure of Glycerin