La Roche-Posay Hyalu B5 Suractivated Serum On your shelf ✓
Maya's readLa Roche-Posay Hyalu B5 Suractivated Serum is a serum built around Glycerin, Pro-vitamin B5 and Hyaluronic acid. It leans strongest on hydration, barrier repair, anti-aging. Best suited to dry, dehydrated and sensitive skin. Go slow — the active is potent enough to irritate if overused.
Skip it if your barrier is already sensitised or compromised: the acids can sting broken or over-exfoliated skin.
What it delivers
How it feels A light, fast-absorbing texture that layers cleanly under the rest of your routine, with no greasy film. — estimated from the formula
What's in it that matters
Classic humectant with strong evidence for improving skin hydration and supporting barrier when combined with emollients.
Humectant and soothing ingredient that helps calm irritation and supports barrier repair and recovery.
Water-binding molecule that increases hydration; works best under occlusive/emollient layers to reduce evaporation.
Purified centella triterpene that calms inflammation supports barrier repair and enhances collagen and elastic fiber remodeling in photoaged skin.
Signal nucleoside that modestly improves periorbital and facial wrinkles and elasticity in Korean cosmetic studies with good tolerability.
Hyaluronic acid cut into shorter fragments, so it sits into the surface rather than resting on top of it. It works with the full-size form rather than replacing it.
Key facts
- Type
- Serum
- Key actives
- Glycerin, Pro-vitamin B5, Hyaluronic acid
- Fragrance
- Contains fragrance
- Fungal-acne (Malassezia) safe
- Not likely — has oils or esters it can feed on
- Pregnancy
- No flagged actives
- Ingredients
- 32 listed
- Typical price
- ~$40, checked July 2026
How to use it
In the evening, and not every night — 2–3 times a week is plenty. Follow with a moisturiser, and wear sunscreen the next day.
Keep it away from
- Retinoids (retinol, tretinoin)
- Benzoyl peroxide
- Other exfoliating acids the same night
Free from
- Paraben-free
Best for
- Dry
- Dehydrated
- Sensitive
- Compromised Barrier
Worth knowing
Nothing our knowledge base would flag: no high-comedogenic or pregnancy-caution actives here.
Common questions
Is La Roche-Posay Hyalu B5 Suractivated Serum good for dry skin?
By our read of the formula, it suits dry, dehydrated, sensitive skin. La Roche-Posay Hyalu B5 Suractivated Serum is a serum built around Glycerin, Pro-vitamin B5 and Hyaluronic acid. It leans strongest on hydration, barrier repair, anti-aging. Best suited to dry, dehydrated and sensitive skin. Go slow — the active is potent enough to irritate if overused.
How do you use La Roche-Posay Hyalu B5 Suractivated Serum?
In the evening, and not every night — 2–3 times a week is plenty. Follow with a moisturiser, and wear sunscreen the next day.
What are the key ingredients in La Roche-Posay Hyalu B5 Suractivated Serum?
The actives that do the work are Glycerin, Pro-vitamin B5, Hyaluronic acid, Madecassoside, Adenosine, Hydrolyzed hyaluronic acid. The rest of the list is texture, preservatives and emulsifiers that hold the formula together.
Against your shelf
Read from your own shelf, in your browser. We never see it.
The full formula, decoded
Every ingredient on the label, in the order it appears (highest amount first). We link the 20 our library knows, name what each one does, and flag anything that can irritate or clog. The rest we leave plain, nothing is hidden.
- Aqua/Water/EauSolvent (base)
- GlycerinHumectant
- Alcohol DenatSolventcan irritate
- Propylene GlycolHumectantmild irritant
- PanthenolHumectant
- Pentylene GlycolHumectant
- DimethiconeOcclusive
- PEG-6 Caprylic/Capric GlyceridesEmulsifier
- Alpinia Galanga Leaf ExtractBotanical extract
- Calcium Chloride
- Glyceryl IsostearateEmollient (ester)
- MadecassosideSoothing
- PPG-6-Decyltetradeceth-30
- Sodium Acetylated Hyaluronate
- Sodium HyaluronateHumectant
- Algin
- AdenosineNucleoside
- Ammonium Polyacryloyldimethyl Taurate
- PropanediolHumectant
- Hydrolyzed Hyaluronic AcidHumectant
- HydroxyacetophenonePreservative
- Caprylic/Capric TriglycerideEmollient
- Caprylyl GlycolPreservative booster
- Citric AcidExfoliantmild irritant
- Trisodium Ethylenediamine DisuccinateChelator (stabiliser)
- Acetyl Glucosamine
- roughly the 1% lineThe rules only require descending order above 1%. From Xanthan Gum down, these 6 can be listed in any order the brand likes, so position stops telling you anything.
- Xanthan GumThickener
- Butylene GlycolHumectant
- 1,2-HexanediolPreservative booster
- TocopherolAntioxidantmild irritant
- PhenoxyethanolPreservativemild irritant
- Parfum/FragranceFragrancecan irritate
Copy the raw INCI list
Aqua/Water/Eau, Glycerin, Alcohol Denat, Propylene Glycol, Panthenol, Pentylene Glycol, Dimethicone, PEG-6 Caprylic/Capric Glycerides, Alpinia Galanga Leaf Extract, Calcium Chloride, Glyceryl Isostearate, Madecassoside, PPG-6-Decyltetradeceth-30, Sodium Acetylated Hyaluronate, Sodium Hyaluronate, Algin, Adenosine, Ammonium Polyacryloyldimethyl Taurate, Propanediol, Hydrolyzed Hyaluronic Acid, Hydroxyacetophenone, Caprylic/Capric Triglyceride, Caprylyl Glycol, Citric Acid, Trisodium Ethylenediamine Disuccinate, Acetyl Glucosamine, Xanthan Gum, Butylene Glycol, 1,2-Hexanediol, Tocopherol, Phenoxyethanol, Parfum/Fragrance
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We don't make or sell skincare of our own. So there's nothing here we're trying to push, just an honest read of whether this formula suits your skin.