Ingredient glossary

Palmitoyl Pentapeptide-4

INCI: Palmitoyl Pentapeptide-4 · Also: Matrixyl, Pal-KTTKS

Solid and proven

A genuinely useful ingredient with real evidence behind it, not hype.

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What it does

  • anti aging
  • firming
  • texture

moderate evidenceDouble blind clinical trials at three ppm report around thirty percent reductions in wrinkle volume with minimal irritation yet replication outside supplier studies is scarce.

On a label: usually effective at 0.0003-0.003%.

Who it's for, and who should skip it

Tends to suit

  • normal
  • dry
  • combo
  • photoaged

Approach with care

No specific group flagged to avoid it.

  • Clogs poresLow
  • Irritation riskLow

Plays well with

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Educational information about a cosmetic ingredient, not medical advice.