Medicube PDRN Pink Peptide Serum

Serum~€30typical, July 2026

Our read, in one look

PDRN is the reason to consider this serum, with Niacinamide behind it.

The case for it

  • PDRN, moderate evidence for lines and firmness
  • Niacinamide, strong evidence for the barrier
  • No alcohol, silicones or parabens

Mind this

  • Morning or evening, whichever suits your routine
  • Isopropyl Myristate: rates high on the pore-clogging scale
  • Add it on its own for a week or two, so you know what your skin is answering to
Best for oily, combo, dry, sensitive skinFind it on amazon.com
Maya's read

Medicube PDRN Pink Peptide Serum is a serum built around Niacinamide, Glycerin and Hyaluronic acid. It leans strongest on hydration, barrier repair, brightening / tone. Best suited to oily, combo and dry skin. One caveat: very breakout-prone skin may find it too rich.

Skip it if you're very breakout-prone: it carries isopropyl myristate, which can clog some pores.

What it delivers

Hydration10
Barrier repair9
Brightening / tone7
Oil-control & blemishes8
Anti-aging7

How it feels A light, fast-absorbing texture that layers cleanly under the rest of your routine, with no greasy film. (estimated from the formula)

What's in it that matters

The molecule doing the workNiacinamideHero Active · strong evidence

Multitasking vitamin that improves barrier, reduces redness, regulates oil, helps with pores and pigmentation with strong clinical support.

  • GlycerinHumectantstrong evidence

    Classic humectant with strong evidence for improving skin hydration and supporting barrier when combined with emollients.

  • Hyaluronic acidHumectantstrong evidence

    Water-binding molecule that increases hydration; works best under occlusive/emollient layers to reduce evaporation.

  • PDRNActive|Supporting Activemoderate evidence

    Biostimulatory nucleotide polymer that improves elasticity hydration and dermal remodeling in injection studies but topical cosmetic data are still limited.

  • GHK-CuActive|Supporting Activemoderate evidence

    Copper-bound tripeptide with genuine repair data, most of it from wound healing rather than from cosmetic trials. Sold on a review its own patent holders wrote.

  • Palmitoyl Pentapeptide-4Active|Supporting Activemoderate evidence

    Lipidated signal peptide that stimulates collagen and matrix components to reduce wrinkles with good tolerability but limited independent long term data.

How to use it

Morning and/or night, after your thinner water-based steps and before heavier creams.

Where it acts

The same cross-section as our 500 dalton page, with this formula's actives on the layer each one works on. Depth is the anatomy's, never an ingredient's.

3 of this product's actives have a layer we can defend. 3 did not, so they are not on the diagram: no source and no honest derivation means no dot.

Sources for the sourced ones: Boo 2021: mechanistic basis for topical nicotinamide; Ebanks et al. 2009: mechanisms regulating skin pigmentation.

Against the average serum

HydrationBarrier repairBrighteningOil-controlAnti-aging
This productMedian serum (20 in catalogue)

It scores higher than the median serum on oil control.

On hydration, brightening and anti-aging it is level with the median, so that is not what sets it apart.

A median, not an average: one unusual formula should not move the middle. The numbers are the same 0 to 10 reads the comparison pages use.

The full ingredients list, decoded

Every ingredient on the label, in the order it appears (highest amount first). We link the 21 our library knows, name what each one does, and flag anything that can irritate or clog. The rest we leave plain, nothing is hidden.

All 40 ingredients, decoded
  1. WaterSolvent (base)
  2. mild irritant
  3. Sodium DnaNucleotide polymer
  4. Millet ExtractBotanical extract
  5. Copper Tripeptide-1Signal peptide
  6. Acetyl Hexapeptide-8Neuromodulating peptide
  7. 1,2-HexanediolPreservative booster
  8. GlycerinHumectant
  9. Dipropylene GlycolHumectant / solvent
  10. Polyglycerin-3Humectant
  11. Glyceryl Acrylate/Acrylic Acid CopolymerThickener
  12. Pvm/Ma Copolymer
  13. EthylhexylglycerinPreservative booster
  14. Glycereth-26Humectant
  15. AdenosineNucleoside
  16. Acrylates/C10-30 Alkyl Acrylate CrosspolymerThickener
  17. may clog pores
  18. UbiquinoneAntioxidant
  19. FragranceFragrance
    can irritate
  20. Caprylyl GlycolPreservative booster
  21. TromethaminepH buffer
  22. Polyisobutene
  23. Caprylyl/Capryl Glucoside
  24. Sorbitan OleateEmulsifier
  25. Atelocollagen
  26. Salmon Egg ExtractBotanical extract
  27. Cyanocobalamin
  28. Melia Azadirachta Leaf ExtractBotanical extract
  29. Melia Azadirachta Flower ExtractBotanical extract
  30. Curcuma Longa (Turmeric) Root ExtractBotanical extract
  31. Ocimum Sanctum Leaf ExtractBotanical extract
  32. Corallina Officinalis ExtractBotanical extract
Copy the raw INCI list

Water, Disodium EDTA, Niacinamide, Hydrolyzed Collagen, Sodium Dna, Millet Extract, Copper Tripeptide-1, Acetyl Hexapeptide-8, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Butylene Glycol, 1,2-Hexanediol, Glycerin, Dipropylene Glycol, Polyglycerin-3, Glyceryl Acrylate/Acrylic Acid Copolymer, Pvm/Ma Copolymer, Sodium Hyaluronate, Ethylhexylglycerin, Glycereth-26, Adenosine, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Isopropyl Myristate, Ubiquinone, Fragrance, Caprylyl Glycol, Tromethamine, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Polyisobutene, Caprylyl/Capryl Glucoside, Sorbitan Oleate, Atelocollagen, Salmon Egg Extract, Cyanocobalamin, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Curcuma Longa (Turmeric) Root Extract, Ocimum Sanctum Leaf Extract, Corallina Officinalis Extract

Read enough? Find it on amazon.com

We don't make or sell skincare of our own. So there's nothing here we're trying to push, just an honest read of whether this formula suits your skin.

Compare it with…

All 11 comparisons

Common questions

Is Medicube PDRN Pink Peptide Serum good for oily skin?

By our read of the formula, it suits oily, combo, dry skin. Medicube PDRN Pink Peptide Serum is a serum built around Niacinamide, Glycerin and Hyaluronic acid. It leans strongest on hydration, barrier repair, brightening / tone. Best suited to oily, combo and dry skin. One caveat: very breakout-prone skin may find it too rich.

How do you use Medicube PDRN Pink Peptide Serum?

Morning and/or night, after your thinner water-based steps and before heavier creams.

What are the key ingredients in Medicube PDRN Pink Peptide Serum?

The actives that do the work are Niacinamide, Glycerin, Hyaluronic acid, PDRN, GHK-Cu, Palmitoyl Pentapeptide-4. The rest of the list is texture, preservatives and emulsifiers that hold the formula together.

What the 3D scene shows

The scene shows Medicube PDRN Pink Peptide Serum beside a cross-section of skin, with 2 of its ingredients drawn at the layer each one acts on and at one shared molecular scale: Glycerin in the stratum corneum, the dead outer layer where most skincare works; Niacinamide in the living epidermis, among the cells that are still dividing. Depths come from the same sourced layer data as the rest of this site, and any ingredient whose layer is not established is left out rather than guessed.

Chemical structure of Niacinamide
Building the scene…

This is skin, in section.

The molecules floating inside it are from this bottle, each at the layer it works on, drawn to one true scale. Drag to turn, pinch or scroll to zoom, tap a molecule for its evidence.

Skin in section· molecules from this formula · one true scale
tap it to decode ↻
PDRN Pink Peptide SerumMedicube · Serum · ~€30

PDRN is the reason to consider this serum, with Niacinamide behind it.

Some links support us, at no cost to you. Where we have not checked a listing we send you to that shop's search, and say so.