Ingredient glossary
PDRN
INCI: Sodium DNA · Also: Polydeoxyribonucleotide
A genuinely useful ingredient with real evidence behind it, not hype.
What it does
- repair
- hydration
- anti aging
strong evidenceA double blind randomized trial of intradermal polydeoxyribonucleotide injections showed significant gains in hydration elasticity and collagen density versus saline yet comparable evidence for topical use is sparse.
Who it's for, and who should skip it
Tends to suit
- normal
- dry
- photoaged
- compromised barrier
Approach with care
- pregnancy
- breastfeeding
- fish allergy
- Clogs poresLow
- Irritation riskLow
Pregnancy: Check with your doctor before using during pregnancy or breastfeeding.
Plays well with
- hyaluronic acid
- vitamin c
- peptides
This, for every label you own
One ingredient is easy. A full label is where it gets confusing. The Ingredient Decoder reads any product and tells you the honest truth, ingredient by ingredient.
Educational information about a cosmetic ingredient, not medical advice.