SKIN1004 Madagascar Centella Azelaic Acid 10 Ampoule

Serum~€19typical, July 2026

Our read, in one look

Azelaic Acid is the reason to consider this serum, with Pro-vitamin B5 behind it.

The case for it

  • Azelaic Acid, moderate evidence for oil and breakouts
  • Pro-vitamin B5, strong evidence for the barrier
  • No fragrance, alcohol, silicones or parabens

Mind this

  • Morning or evening, whichever suits your routine
  • Add it on its own for a week or two, so you know what your skin is answering to
Best for acne prone, rosacea, pigmentation, oily skinFind it on amazon.com
Maya's read

SKIN1004 Madagascar Centella Azelaic Acid 10 Ampoule is a serum built around Azelaic Acid, Glycerin and Pro-vitamin B5. It leans strongest on hydration, barrier repair, brightening / tone. Best suited to acne prone, rosacea and pigmentation skin. Nothing in it we'd flag for most people.

Skip it if you already own something similar: it's a solid, honest basic rather than a must-have upgrade.

The formula, drawn

Every ingredient in label order, coloured by the job it does here.

13 of the 27 sit above the 1% line. The other 14, hatched, are each under 1%. Widths show the ORDER on the label and nothing else: the label never discloses amounts, so we never draw them.

  • Actives & signals
  • Hydrators
  • Texture & base
  • Preservation
  • Not in our library yet
  • No fragrance anywhere on the label

What it delivers

Hydration10
Barrier repair8
Brightening / tone8
Oil-control & blemishes9
Anti-aging6

How it feels A light, fast-absorbing texture that layers cleanly under the rest of your routine, with no greasy film. (estimated from the formula)

What's in it that matters

The molecule doing the workAzelaic AcidHero Active · moderate evidence

Multifunctional dicarboxylic acid with antibacterial, anti-inflammatory and tyrosinase-inhibiting activity that treats acne, rosacea and hyperpigmentation.

  • GlycerinHumectantstrong evidence

    Classic humectant with strong evidence for improving skin hydration and supporting barrier when combined with emollients.

  • Pro-vitamin B5Supporting Activestrong evidence

    Humectant and soothing ingredient that helps calm irritation and supports barrier repair and recovery.

  • Hyaluronic acidHumectantstrong evidence

    Water-binding molecule that increases hydration; works best under occlusive/emollient layers to reduce evaporation.

  • AllantoinSupporting Activestrong evidence

    Soothing ingredient that helps calm irritation and support surface healing in compromised skin.

  • Centella Asiatica ExtractSupporting Activestrong evidence

    Plant extract rich in triterpenes that promotes wound healing reduces redness and supports barrier repair in irritated or scar prone skin.

How to use it

Morning and/or night, after your thinner water-based steps and before heavier creams.

Where it acts

The same cross-section as our 500 dalton page, with this formula's actives on the layer each one works on. Depth is the anatomy's, never an ingredient's.

4 of this product's actives have a layer we can defend. 2 did not, so they are not on the diagram: no source and no honest derivation means no dot.

Sources for the sourced ones: Ebanks et al. 2009: mechanisms regulating skin pigmentation; StatPearls: Acne Vulgaris.

Against the average serum

HydrationBarrier repairBrighteningOil-controlAnti-aging
This productMedian serum (20 in catalogue)

It scores higher than the median serum on oil control.

On hydration, barrier repair and anti-aging it is level with the median, so that is not what sets it apart.

A median, not an average: one unusual formula should not move the middle. The numbers are the same 0 to 10 reads the comparison pages use.

The full ingredients list, decoded

Every ingredient on the label, in the order it appears (highest amount first). We link the 15 our library knows, name what each one does, and flag anything that can irritate or clog. The rest we leave plain, nothing is hidden.

All 27 ingredients, decoded
  1. WaterSolvent (base)
  2. Azelaic AcidDicarboxylic acid
    mild irritant
  3. Hydroxypropyl Cyclodextrin
  4. Disodium PhosphatepH buffer
  5. PropanediolHumectant
  6. Potassium Azeloyl Diglycinate
  7. Maltodextrin
  8. Azelamide Mea
  9. PanthenolHumectant
  10. 1,2-HexanediolPreservative booster
  11. GlycerinHumectant
  12. roughly the 1% lineThe rules only require descending order above 1%. From Ethylhexylglycerin down, these 14 can be listed in any order the brand likes, so position stops telling you anything.
  13. EthylhexylglycerinPreservative booster
  14. AllantoinSoothing
  15. Melia Azadirachta Leaf ExtractBotanical extract
  16. Biosaccharide Gum-1
  17. Melia Azadirachta Flower ExtractBotanical extract
  18. Beta-GlucanHumectant
  19. Centella Asiatica Leaf ExtractBotanical extract
  20. Phellinus Linteus ExtractBotanical extract
  21. TocopherolAntioxidant
    mild irritant
  22. Citric AcidExfoliant
    mild irritant
  23. Sodium CitratePh adjuster
  24. Glycyrrhiza Glabra (Licorice) Root ExtractBotanical extract

Worth knowing: Allantoin, Centella Asiatica Extract sit below that line. They are in there, and the label does not tell you how much. That is not the same as saying it is too little to matter.

Copy the raw INCI list

Water, Azelaic Acid, Hydroxypropyl Cyclodextrin, Disodium Phosphate, Pentylene Glycol, Propanediol, Potassium Azeloyl Diglycinate, Maltodextrin, Azelamide Mea, Panthenol, Butylene Glycol, 1,2-Hexanediol, Glycerin, Ethylhexylglycerin, Allantoin, Centella Asiatica Extract, Melia Azadirachta Leaf Extract, Biosaccharide Gum-1, Sodium Hyaluronate, Melia Azadirachta Flower Extract, Beta-Glucan, Centella Asiatica Leaf Extract, Phellinus Linteus Extract, Tocopherol, Citric Acid, Sodium Citrate, Glycyrrhiza Glabra (Licorice) Root Extract

Read enough? Find it on amazon.com

We don't make or sell skincare of our own. So there's nothing here we're trying to push, just an honest read of whether this formula suits your skin.

Common questions

Is SKIN1004 Madagascar Centella Azelaic Acid 10 Ampoule good for acne prone skin?

By our read of the formula, it suits acne prone, rosacea, pigmentation skin. SKIN1004 Madagascar Centella Azelaic Acid 10 Ampoule is a serum built around Azelaic Acid, Glycerin and Pro-vitamin B5. It leans strongest on hydration, barrier repair, brightening / tone. Best suited to acne prone, rosacea and pigmentation skin. Nothing in it we'd flag for most people.

How do you use SKIN1004 Madagascar Centella Azelaic Acid 10 Ampoule?

Morning and/or night, after your thinner water-based steps and before heavier creams.

What are the key ingredients in SKIN1004 Madagascar Centella Azelaic Acid 10 Ampoule?

The actives that do the work are Azelaic Acid, Glycerin, Pro-vitamin B5, Hyaluronic acid, Allantoin, Centella Asiatica Extract. The rest of the list is texture, preservatives and emulsifiers that hold the formula together.

Does SKIN1004 Madagascar Centella Azelaic Acid 10 Ampoule contain fragrance?

No. By our reading of the ingredient list it is fragrance-free, which is a plus for sensitive or reactive skin.

What the 3D scene shows

The scene shows SKIN1004 Madagascar Centella Azelaic Acid 10 Ampoule beside a cross-section of skin, with 3 of its ingredients drawn at the layer each one acts on and at one shared molecular scale: Glycerin and Pro-vitamin B5 in the stratum corneum, the dead outer layer where most skincare works; Azelaic Acid in the living epidermis, among the cells that are still dividing. Depths come from the same sourced layer data as the rest of this site, and any ingredient whose layer is not established is left out rather than guessed.

Chemical structure of Azelaic Acid
Building the scene…

This is skin, in section.

The molecules floating inside it are from this bottle, each at the layer it works on, drawn to one true scale. Drag to turn, pinch or scroll to zoom, tap a molecule for its evidence.

Skin in section· molecules from this formula · one true scale
tap it to decode ↻
Madagascar Centella Azelaic Acid 10 AmpouleSKIN1004 · Serum · ~€19

Azelaic Acid is the reason to consider this serum, with Pro-vitamin B5 behind it.

Some links support us, at no cost to you. Where we have not checked a listing we send you to that shop's search, and say so.