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Anua Niacinamide 10% + TXA 4% Serum vs SKIN1004 Madagascar Centella Ampoule

Same comparison whichever way you searched it: SKIN1004 Madagascar Centella Ampoule vs Anua Niacinamide 10% + TXA 4% Serum.

The bottom line

Anua Niacinamide 10% + TXA 4% Serum does more across the board (it leads on barrier repair, brightening / tone, oil-control & blemishes), while SKIN1004 Madagascar Centella Ampoule is the simpler, more pared-back pick.

Reach for Anua Niacinamide 10% + TXA 4% Serum if you want the actives; SKIN1004 Madagascar Centella Ampoule if you want fewer ingredients doing less, gently.

Reviewed by Maya FaourLast reviewed September 2026
Anua Niacinamide 10% + TXA 4% SerumAnuaNiacinamide 10% + TXA 4% SerumSerum · ~€20See every ingredient in Niacinamide 10% + TXA 4% Serum, decoded
SKIN1004 Madagascar Centella AmpouleSKIN1004Madagascar Centella AmpouleSerum · ~€18See every ingredient in Madagascar Centella Ampoule, decoded

Which should you pick?

Pick Niacinamide 10% + TXA 4% Serum if

  • dark spots, dullness or an uneven tone are your focus
  • you are dealing with breakouts and oiliness
  • you want more actives working at once

Pick Madagascar Centella Ampoule if

  • you want the more affordable option
  • you are prone to fungal acne (malassezia)
  • you prefer a simpler, more minimal formula

What each delivers

HydrationBarrierBrighteningOil-controlAnti-aging
Niacinamide 10% + TXA 4% SerumMadagascar Centella Ampoule
  • Hydration
    1010
  • Barrier repair
    107
  • Brightening / tone
    92
  • Oil-control & blemishes
    83
  • Anti-aging
    65

Side by side

Niacinamide 10% + TXA 4% SerumMadagascar Centella Ampoule
TypeSerumSerum
Key activesGlycerin, Niacinamide 10%, Ceramide 3Glycerin, Centella Asiatica Extract
TextureA light, fast-absorbing texture that layers cleanly under the rest of your routine, with no greasy film.A light, fast-absorbing texture that layers cleanly under the rest of your routine, with no greasy film.
FragranceNone detectedNone detected
Fungal-acne safeNot likelyLikely
PregnancyNo flagged activesNo flagged actives
Ingredients51 listed7 listed
Price~€20~€18

What's in one but not the other

The two labels share 5 of the 53 ingredients between them. The actives are where they part company.

What each one adds acts on The living epidermis, The stratum corneum for Anua Niacinamide 10% + TXA 4% Serum and Not established for SKIN1004 Madagascar Centella Ampoule. That is the layer each is understood to act on, not how deep it travels.

Only in Niacinamide 10% + TXA 4% Serum

Both share

Only in Madagascar Centella Ampoule

The molecule doing the work

Niacinamide 10% + TXA 4% SerumGlycerin
Madagascar Centella AmpouleGlycerin

Better for…

  • Dark spots & uneven toneNiacinamide 10% + TXA 4% Serum
  • Breakouts & congestionNiacinamide 10% + TXA 4% Serum
  • Dryness & dehydrationEither works

SKIN1004 Madagascar Centella Ampoule is the cheaper of the two (~€18 vs ~€20).

Ready to pick one?

Niacinamide 10% + TXA 4% Serum on amazon.comMadagascar Centella Ampoule on amazon.com

Affiliate links, so a purchase sends us a small commission at no extra cost to you. As an Amazon Associate, Glow Simplified earns from qualifying purchases. We make and sell nothing here, so the verdict above never bends toward a sale.

Common questions

Is Anua Niacinamide 10% + TXA 4% Serum or SKIN1004 Madagascar Centella Ampoule better for dark spots & uneven tone?

For dark spots & uneven tone, Anua Niacinamide 10% + TXA 4% Serum is the stronger pick by our read of the two formulas. Anua Niacinamide 10% + TXA 4% Serum does more across the board (it leads on barrier repair, brightening / tone, oil-control & blemishes), while SKIN1004 Madagascar Centella Ampoule is the simpler, more pared-back pick. Reach for Anua Niacinamide 10% + TXA 4% Serum if you want the actives; SKIN1004 Madagascar Centella Ampoule if you want fewer ingredients doing less, gently.

Which is cheaper, Anua Niacinamide 10% + TXA 4% Serum or SKIN1004 Madagascar Centella Ampoule?

SKIN1004 Madagascar Centella Ampoule is the cheaper of the two (~€18 vs ~€20).

Can I use Anua Niacinamide 10% + TXA 4% Serum and SKIN1004 Madagascar Centella Ampoule together?

They are both serums, so you would normally pick one rather than layer both in the same step. You can keep both and alternate them (morning and night, or on different days) if you like variety, but you do not need two.

Compare it with…

VSCeraVeResurfacing Retinol SerumShares Ceramide 3 and NiacinamideVSBeauty of JoseonGlow Serum: Propolis + NiacinamideShares Centella Asiatica ExtractVSCeraVeSkin Renewing Retinol SerumShares Ceramide 3 and Niacinamide
All 41 comparisons